Departure Ports

Colon (Panama)

Cruises from Colon (Panama)

Compare cruise prices departing from Colon (Panama). 1 cruise lines, prices from €92.

69 cruises available

Prices from 92

2 ships

6 markets

Track Cruises monitors 69 cruises departing from Colon (Panama) across 1 cruise lines and 6 international markets. Prices start from €92 per person. Compare departure dates, cabin types, and itineraries to find the best deal from Colon (Panama).

About Colon (Panama)

Colon sits at the Caribbean entrance of the Panama Canal, making it one of the world's most strategically important cruise ports. Passengers transiting the canal witness one of engineering's greatest achievements, while the nearby ruins of Portobelo and the fortress of San Lorenzo reveal centuries of colonial history.

What to See Nearby

Panama Canal LocksSan Lorenzo FortPortobelo RuinsGatun Lake

Southern Caribbean Cruise

Serenade of the Seas

Caribbean

DepartureApr 18, 2026

Duration1 day

Best Price (Netherlands)

€92EUR per person

5 markets

Colon To San Juan Cruise

Grandeur of the Seas

Repositioning

DepartureApr 24, 2027

Duration7 days

Best Price (Australia)

A$1,003AUD per person

1 market

€600 EUR

Southern Caribbean Cruise

Grandeur of the Seas

Caribbean

DepartureJun 27, 2026

Duration7 days

Best Price (USA)

$748USD per person

6 markets

€649 EUR

Southern Caribbean Cruise

Grandeur of the Seas

Caribbean

DepartureJun 06, 2026

Duration7 days

Best Price (USA)

$773USD per person

6 markets

€671 EUR

Panama Canal Westward Cruise

Serenade of the Seas

Panama Canal

DepartureApr 25, 2026

Duration10 days

Best Price (Germany)

€686EUR per person

5 markets

Southern Caribbean Cruise

Grandeur of the Seas

Caribbean

DepartureJun 13, 2026

Duration7 days

Best Price (USA)

$798USD per person

6 markets

€692 EUR

Southern Caribbean Cruise

Grandeur of the Seas

Caribbean

DepartureFeb 05, 2028

Duration7 days

Best Price (Germany)

€726EUR per person

6 markets

Southern Caribbean Cruise

Grandeur of the Seas

Caribbean

DepartureFeb 12, 2028

Duration7 days

Best Price (Germany)

€726EUR per person

6 markets

Southern Caribbean Cruise

Grandeur of the Seas

Caribbean

DepartureFeb 26, 2028

Duration7 days

Best Price (Germany)

€726EUR per person

6 markets

Southern Caribbean Cruise

Grandeur of the Seas

Caribbean

DepartureFeb 19, 2028

Duration7 days

Best Price (Germany)

€728EUR per person

6 markets

Southern Caribbean Cruise

Grandeur of the Seas

Caribbean

DepartureJan 22, 2028

Duration7 days

Best Price (Germany)

€743EUR per person

6 markets

Southern Caribbean Cruise

Grandeur of the Seas

Caribbean

DepartureJan 29, 2028

Duration7 days

Best Price (Germany)

€743EUR per person

6 markets

Southern Caribbean Cruise

Grandeur of the Seas

Caribbean

DepartureJan 15, 2028

Duration7 days

Best Price (Germany)

€745EUR per person

6 markets

Southern Caribbean Cruise

Grandeur of the Seas

Caribbean

DepartureJan 08, 2028

Duration7 days

Best Price (Germany)

€745EUR per person

6 markets

Southern Caribbean Cruise

Grandeur of the Seas

Caribbean

DepartureAug 29, 2026

Duration7 days

Best Price (Germany)

€745EUR per person

6 markets

Southern Caribbean Cruise

Grandeur of the Seas

Caribbean

DepartureSep 12, 2026

Duration7 days

Best Price (USA)

$867USD per person

6 markets

€752 EUR

Southern Caribbean Cruise

Grandeur of the Seas

Caribbean

DepartureApr 03, 2027

Duration7 days

Best Price (Germany)

€759EUR per person

6 markets

Southern Caribbean Cruise

Grandeur of the Seas

Caribbean

DepartureApr 22, 2028

Duration7 days

Best Price (Germany)

€760EUR per person

6 markets

Southern Caribbean Cruise

Grandeur of the Seas

Caribbean

DepartureMar 06, 2027

Duration7 days

Best Price (Germany)

€766EUR per person

6 markets

Southern Caribbean Cruise

Grandeur of the Seas

Caribbean

DepartureMay 23, 2026

Duration7 days

Best Price (USA)

$885USD per person

6 markets

€768 EUR

Southern Caribbean Cruise

Grandeur of the Seas

Caribbean

DepartureSep 26, 2026

Duration7 days

Best Price (USA)

$890USD per person

6 markets

€772 EUR

Southern Caribbean Cruise

Grandeur of the Seas

Caribbean

DepartureDec 04, 2027

Duration7 days

Best Price (Germany)

€778EUR per person

6 markets

Southern Caribbean Cruise

Grandeur of the Seas

Caribbean

DepartureJun 20, 2026

Duration7 days

Best Price (USA)

$897USD per person

6 markets

€778 EUR

Southern Caribbean Cruise

Grandeur of the Seas

Caribbean

DepartureOct 24, 2026

Duration7 days

Best Price (UK)

£681GBP per person

6 markets

€779 EUR

View All Cruises from Colon (Panama)