Departure Ports

Palermo

Cruises from Palermo

Compare cruise prices departing from Palermo. 2 cruise lines, prices from €259.

264 cruises available

Prices from 259

10 ships

6 markets

Track Cruises monitors 264 cruises departing from Palermo across 2 cruise lines and 6 international markets. Prices start from €259 per person. Compare departure dates, cabin types, and itineraries to find the best deal from Palermo.

About Palermo

Palermo, the capital of Sicily, is a captivating cruise port where Arab-Norman architecture, bustling street markets, and legendary Sicilian cuisine converge. Cruises departing from or calling at Palermo explore the central and western Mediterranean, with connections to the Amalfi Coast, Malta, and Tunisia.

What to See Nearby

Palermo CathedralTeatro MassimoMondello BeachMonreale Cathedral

Westliches Mittelmeer ab Palermo

Costa Smeralda

Mediterranean

DepartureApr 30, 2026

Duration4 days

Best Price (Germany)

€259EUR per person

6 markets

Mediterraneo Orientale da Palermo

Costa Pacifica

Mediterranean

DepartureApr 12, 2027

Duration5 days

Best Price (Italy)

€349EUR per person

1 market

Westliches Mittelmeer ab Palermo

Costa Fascinosa

Mediterranean

DepartureSep 16, 2026

Duration5 days

Best Price (UK)

£309GBP per person

6 markets

€355 EUR

Western Mediterranean from Palermo

Costa Smeralda

Mediterranean

DepartureApr 30, 2026

Duration8 days

Best Price (Italy)

€449EUR per person

2 markets

Mittelmeer

MSC Splendida

Mediterranean

DepartureMay 14, 2026

Duration7 days

Best Price (Italy)

€449EUR per person

5 markets

Western Mediterranean from Palermo

Costa Smeralda

Mediterranean

DepartureMay 07, 2026

Duration8 days

Best Price (Italy)

€479EUR per person

2 markets

Mediterranean

MSC Splendida

Mediterranean

DepartureMay 21, 2026

Duration7 days

Best Price (Italy)

€499EUR per person

3 markets

Mediterranean

MSC Meraviglia

Mediterranean

DepartureMay 08, 2026

Duration7 days

Best Price (Italy)

€499EUR per person

3 markets

Western Mediterranean from Palermo

Costa Smeralda

Mediterranean

DepartureMay 14, 2026

Duration8 days

Best Price (Italy)

€499EUR per person

2 markets

Mittelmeer

MSC Meraviglia

Mediterranean

DepartureMay 15, 2026

Duration7 days

Best Price (Italy)

€519EUR per person

5 markets

Mediterranean

MSC Splendida

Mediterranean

DepartureMay 28, 2026

Duration7 days

Best Price (Italy)

€519EUR per person

2 markets

Mittelmeer

MSC Seaview

Mediterranean

DepartureMay 18, 2026

Duration7 days

Best Price (Italy)

€529EUR per person

5 markets

Mediterranean

MSC Meraviglia

Mediterranean

DepartureMay 22, 2026

Duration7 days

Best Price (Italy)

€539EUR per person

1 market

Mediterranean

MSC Euribia

Mediterranean

DepartureFeb 10, 2027

Duration7 days

Best Price (Italy)

€549EUR per person

2 markets

Mediterranean

MSC Euribia

Mediterranean

DepartureJan 20, 2027

Duration7 days

Best Price (Italy)

€549EUR per person

2 markets

Mittelmeer

MSC Seaview

Mediterranean

DepartureMay 25, 2026

Duration7 days

Best Price (Italy)

€549EUR per person

5 markets

Mediterranean

MSC Euribia

Mediterranean

DepartureJan 13, 2027

Duration7 days

Best Price (Italy)

€549EUR per person

2 markets

Western Mediterranean from Palermo

Costa Smeralda

Mediterranean

DepartureMay 21, 2026

Duration8 days

Best Price (Italy)

€549EUR per person

2 markets

Mediterranean

MSC Euribia

Mediterranean

DepartureFeb 17, 2027

Duration7 days

Best Price (Italy)

€549EUR per person

2 markets

Mittelmeer

MSC Splendida

Mediterranean

DepartureMay 07, 2026

Duration7 days

Best Price (Germany)

€559EUR per person

4 markets

Western Mediterranean from Palermo

Costa Smeralda

Mediterranean

DepartureMay 28, 2026

Duration8 days

Best Price (Italy)

€579EUR per person

2 markets

Mittelmeer

MSC Splendida

Mediterranean

DepartureOct 15, 2026

Duration7 days

Best Price (Italy)

€579EUR per person

4 markets

Western Mediterranean from Palermo

Costa Toscana

Mediterranean

DepartureJan 07, 2027

Duration8 days

Best Price (Italy)

€579EUR per person

2 markets

Western Mediterranean from Palermo

Costa Toscana

Mediterranean

DepartureJan 14, 2027

Duration8 days

Best Price (Italy)

€579EUR per person

2 markets

View All Cruises from Palermo