Departure Ports

San Diego

Cruises from San Diego

Compare cruise prices departing from San Diego. 5 cruise lines, prices from €209.

129 cruises available

Prices from 209

10 ships

13 markets

Track Cruises monitors 129 cruises departing from San Diego across 5 cruise lines and 13 international markets. Prices start from €209 per person. Compare departure dates, cabin types, and itineraries to find the best deal from San Diego.

About San Diego

San Diego offers one of the most pleasant cruise departures on the West Coast, with year-round sunshine and the vibrant Gaslamp Quarter steps from the terminal. Home to the world-famous San Diego Zoo and beautiful Coronado Beach, cruises from here head south to the Mexican Riviera or north toward Hawaii.

What to See Nearby

Balboa ParkSan Diego ZooGaslamp QuarterCoronado Beach

Ensenada Cruise

from€209/pp

Ensenada Cruise

Serenade of the Seas

Mexico

Oct 02, 2026

·

2 nights

9 markets

≈ €209

Ensenada Cruise

from€241/pp

Ensenada Cruise

Serenade of the Seas

Mexico

Dec 10, 2026

·

3 nights

9 markets

≈ €241

Ensenada Cruise

from€249/pp

Ensenada Cruise

Serenade of the Seas

Mexico

Dec 03, 2026

·

3 nights

9 markets

≈ €249

Ensenada Cruise

from€258/pp

Ensenada Cruise

Serenade of the Seas

Mexico

Jan 21, 2027

·

3 nights

9 markets

≈ €258

Ensenada Cruise

from€258/pp

Ensenada Cruise

Serenade of the Seas

Mexico

Jan 14, 2027

·

3 nights

9 markets

≈ €258

Catalina & Ensenada Cruise

from€259/pp

Catalina & Ensenada Cruise

Serenade of the Seas

Mexico

Jan 10, 2027

·

4 nights

9 markets

≈ €259

Ensenada Cruise

from€266/pp

Ensenada Cruise

Serenade of the Seas

Mexico

Oct 15, 2026

·

3 nights

9 markets

≈ €266

Catalina & Ensenada Cruise

from€268/pp

Catalina & Ensenada Cruise

Serenade of the Seas

Mexique

Nov 29, 2026

·

4 nights

9 markets

≈ €268

Ensenada Cruise

from€275/pp

Ensenada Cruise

Serenade of the Seas

Mexico

Feb 18, 2027

·

3 nights

9 markets

≈ €275

Ensenada Cruise

from€275/pp

Ensenada Cruise

Serenade of the Seas

Mexico

Feb 25, 2027

·

3 nights

9 markets

≈ €275

Ensenada Cruise

from€275/pp

Ensenada Cruise

Serenade of the Seas

Mexico

Feb 04, 2027

·

3 nights

9 markets

≈ €275

Catalina & Ensenada Cruise

from€276/pp

Catalina & Ensenada Cruise

Serenade of the Seas

Mexique

Feb 07, 2027

·

4 nights

9 markets

≈ €276

Catalina & Ensenada Cruise

from€276/pp

Catalina & Ensenada Cruise

Serenade of the Seas

Mexique

Jan 24, 2027

·

4 nights

9 markets

≈ €276

Catalina & Ensenada Cruise

from€276/pp

Catalina & Ensenada Cruise

Serenade of the Seas

Mexico

Jan 17, 2027

·

4 nights

9 markets

≈ €276

Catalina & Ensenada Cruise

from€276/pp

Catalina & Ensenada Cruise

Serenade of the Seas

Mexico

Dec 06, 2026

·

4 nights

9 markets

≈ €276

Ensenada Cruise

from€283/pp

Ensenada Cruise

Serenade of the Seas

Mexico

Feb 11, 2027

·

3 nights

9 markets

≈ €283

Catalina & Ensenada Cruise

from€285/pp

Catalina & Ensenada Cruise

Serenade of the Seas

Mexico

Feb 14, 2027

·

4 nights

9 markets

≈ €285

Catalina & Ensenada Cruise

from€285/pp

Catalina & Ensenada Cruise

Serenade of the Seas

Mexico

Feb 21, 2027

·

4 nights

9 markets

≈ €285

Catalina & Ensenada Cruise

30-day low

from€287/pp

Catalina & Ensenada Cruise

Serenade of the Seas

Mexico

Oct 11, 2026

·

4 nights

9 markets

≈ €287

Ensenada Cruise

from€289/pp

Ensenada Cruise

Serenade of the Seas

Mexico

Mar 11, 2027

·

3 nights

9 markets

≈ €289

Ensenada Cruise

from€290/pp

Ensenada Cruise

Serenade of the Seas

Mexico

Mar 18, 2027

·

3 nights

9 markets

≈ €290

Ensenada Cruise

from€290/pp

Ensenada Cruise

Serenade of the Seas

Mexico

Mar 25, 2027

·

3 nights

9 markets

≈ €290

Catalina & Ensenada Cruise

from€299/pp

Catalina & Ensenada Cruise

Serenade of the Seas

Mexico

Mar 21, 2027

·

4 nights

9 markets

≈ €299

Catalina & Ensenada Cruise

from€302/pp

Catalina & Ensenada Cruise

Serenade of the Seas

Mexico

Mar 07, 2027

·

4 nights

9 markets

≈ €302

View All Cruises from San Diego