Departure Ports

San Diego

Cruises from San Diego

Compare cruise prices departing from San Diego. 4 cruise lines, prices from €169.

65 cruises available

Prices from 169

8 ships

7 markets

Track Cruises monitors 65 cruises departing from San Diego across 4 cruise lines and 7 international markets. Prices start from €169 per person. Compare departure dates, cabin types, and itineraries to find the best deal from San Diego.

About San Diego

San Diego offers one of the most pleasant cruise departures on the West Coast, with year-round sunshine and the vibrant Gaslamp Quarter steps from the terminal. Home to the world-famous San Diego Zoo and beautiful Coronado Beach, cruises from here head south to the Mexican Riviera or north toward Hawaii.

What to See Nearby

Balboa ParkSan Diego ZooGaslamp QuarterCoronado Beach

4-DAY PACIFIC COASTAL CRUISE

Zaandam

Pacific

DepartureMay 02, 2026

Duration4 days

Best Price (Canada)

272CAD per person

7 markets

€169 EUR

4-DAY PACIFIC COASTAL CRUISE

Eurodam

Pacific

DepartureApr 20, 2026

Duration4 days

Best Price (Canada)

332CAD per person

7 markets

€207 EUR

Ensenada Cruise

Serenade of the Seas

Mexico

DepartureOct 02, 2026

Duration2 days

Best Price (USA)

$333USD per person

6 markets

€289 EUR

Ensenada Cruise

Serenade of the Seas

Mexico

DepartureJan 14, 2027

Duration3 days

Best Price (USA)

$336USD per person

6 markets

€292 EUR

Ensenada Cruise

Serenade of the Seas

Mexico

DepartureJan 21, 2027

Duration3 days

Best Price (USA)

$337USD per person

6 markets

€292 EUR

5-DAY PACIFIC COASTAL CRUISE

Koningsdam

Pacific

DepartureApr 27, 2026

Duration5 days

Best Price (Canada)

480CAD per person

7 markets

€299 EUR

Ensenada Cruise

Serenade of the Seas

Mexico

DepartureFeb 11, 2027

Duration3 days

Best Price (USA)

$346USD per person

6 markets

€300 EUR

Ensenada Cruise

Serenade of the Seas

Mexico

DepartureFeb 25, 2027

Duration3 days

Best Price (USA)

$346USD per person

6 markets

€300 EUR

Ensenada Cruise

Serenade of the Seas

Mexico

DepartureFeb 18, 2027

Duration3 days

Best Price (USA)

$347USD per person

6 markets

€301 EUR

Ensenada Cruise

Serenade of the Seas

Mexico

DepartureFeb 04, 2027

Duration3 days

Best Price (USA)

$347USD per person

6 markets

€301 EUR

Ensenada Cruise

Serenade of the Seas

Mexico

DepartureDec 10, 2026

Duration3 days

Best Price (USA)

$349USD per person

6 markets

€302 EUR

Ensenada Cruise

Serenade of the Seas

Mexico

DepartureDec 03, 2026

Duration3 days

Best Price (USA)

$349USD per person

6 markets

€302 EUR

Ensenada Cruise

Serenade of the Seas

Mexico

DepartureMar 11, 2027

Duration3 days

Best Price (USA)

$357USD per person

6 markets

€309 EUR

Ensenada Cruise

Serenade of the Seas

Mexico

DepartureMar 25, 2027

Duration3 days

Best Price (USA)

$357USD per person

6 markets

€310 EUR

Ensenada Cruise

Serenade of the Seas

Mexico

DepartureMar 18, 2027

Duration3 days

Best Price (USA)

$357USD per person

6 markets

€310 EUR

Ensenada Cruise

Serenade of the Seas

Mexico

DepartureOct 15, 2026

Duration3 days

Best Price (USA)

$369USD per person

6 markets

€320 EUR

Catalina & Ensenada Cruise

Serenade of the Seas

Mexico

DepartureDec 06, 2026

Duration4 days

Best Price (USA)

$376USD per person

6 markets

€326 EUR

Catalina & Ensenada Cruise

Serenade of the Seas

Mexico

DepartureFeb 07, 2027

Duration4 days

Best Price (USA)

$394USD per person

6 markets

€342 EUR

Catalina & Ensenada Cruise

Serenade of the Seas

Mexico

DepartureFeb 21, 2027

Duration4 days

Best Price (USA)

$395USD per person

6 markets

€342 EUR

Catalina & Ensenada Cruise

Serenade of the Seas

Mexico

DepartureJan 17, 2027

Duration4 days

Best Price (USA)

$395USD per person

6 markets

€342 EUR

Catalina & Ensenada Cruise

Serenade of the Seas

Mexico

DepartureFeb 14, 2027

Duration4 days

Best Price (USA)

$395USD per person

6 markets

€342 EUR

Catalina & Ensenada Cruise

Serenade of the Seas

Mexico

DepartureJan 10, 2027

Duration4 days

Best Price (USA)

$395USD per person

6 markets

€343 EUR

Catalina & Ensenada Cruise

Serenade of the Seas

Mexico

DepartureJan 24, 2027

Duration4 days

Best Price (USA)

$395USD per person

6 markets

€343 EUR

Catalina & Ensenada Cruise

Serenade of the Seas

Mexico

DepartureNov 29, 2026

Duration4 days

Best Price (USA)

$395USD per person

6 markets

€343 EUR

View All Cruises from San Diego